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Original research articles as references

  • Kadomatsu, K., Tomomura, M. and Muramatsu, T. (1988) cDNA cloning and sequencing of a new gene intensely expressed in early differentiation stages of embryonal carcinoma cells and in mid-gestation period of mouse embryogenesis. Biochem. Biophys. Res. Commun. 151, 1312-1318. [PMID: 3355557]
  • Vigny, M., Raulais, D., Puzenat, N., Duprez, D., Hartmann, M. P., Jeanny, J. C., and Courtois, Y. (1989) Identification of a new heparin-binding protein localized within chick basement membranes. Eur. J. Biochem. 186, 733-740. [PMID: 2558016]
  • Kadomatsu, K., Huang, R.. P., Suganuma, T., Murata, F. and Muramatsu, T. (1990) A retinoic acid responsive gene MK found in the teratocarcinoma system is expressed in spatially and temporally controlled manner during mouse embryogenesis. J. Cell Biol. 110, 607-616. [PMID: 1689730]
  • Tomomura, M., Kadomatsu, K., Matsubara, S. and Muramatsu, T. (1990) A retinoic acid-responsive gene, MK, found in the teratocarcinoma system. Heterogeneity of the transcript and the nature of the translation product. J. Biol. Chem. 265, 10765-10770. [PMID: 2355021]
  • Merenmies, J. and Rauvala, H. (1990) Molecular cloning of the 18-kDa growth-associated protein of developing brain. J. Biol. Chem. 265, 16721-16724. [PMID: 2170351]
  • Li, Y. S., Milner, P. G., Chauhan, A. K., Watson, M. A., Hoffman, R. M., Kodner, C. M., Milbrandt, J. and Deuel, T. F. (1990) Cloning and expression of a developmentally regulated protein that induces mitogenic and neurite outgrowth activity. Science 250, 1690-1694. [PMID: 2270483]
  • Matsubara, S., Tomomura, M., Kadomatsu, K. and Muramatsu, T. (1990) Structure of a retinoic acid-responsive gene, MK, which is transiently activated during the differentiation of embryonal carcinoma cells and the mid-gestation period of mouse embryogenesis. J. Biol. Chem. 265, 9441-9443. [PMID: 2345177]
  • Tomomura, M., Kadomatsu, K., Nakamoto, M., Muramatsu, H., Kondoh, H., Imagawa, K. and Muramatsu, T. (1990) A retinoic acid responsive gene, MK, produces a secreted protein with heparin binding activity. Biochem. Biophys. Res. Commun. 171, 603-609. [PMID: 2403350]
  • Muramatsu, H. and Muramatsu, T. (1991) Purification of recombinant midkine and examination of its biological activities: functional comparison of new heparin binding factors. Biochem. Biophys. Res. Commun. 177, 652-658. [PMID: 2049087]
  • Tsutsui, J., Uehara, K., Kadomatsu, K., Matsubara, S. and Muramatsu, T. (1991) A new family of heparin-binding factors: strong conservation of midkine (MK) sequences between the human and the mouse. Biochem. Biophys. Res. Commun. 176, 792-797. [PMID: 2025291]
  • Raulais, D., Lagente-Chevallier, O., Guettet, C., Duprez, D., Courtois, Y. and Vigny, M. (1991) A new heparin-binding protein regulated by retinoic acid from chick embryos. Biochem. Biophys. Res. Commun. 174, 708-715 [PMID: 1993066]
  • Simon-Chazottes, D., Matsubara, S., Miyauchi, T., Muramatsu, T. and Guenet, J. L. (1992) Chromosomal localization of two cell-surface associated molecules of potential importance in development: midkine (Mdk) and basigin (Bsg). Mamm. Genome 2, 269-271. [PMID: 1347477]
  • Nurcombe, V., Fraser, N., Herlaar, E. and Heath, J.K. (1992) MK: a pluripotential embryonic stem-cell-derived neuroregulatory factor. Development. 116, 1175-1183. [PMID: 1295735]
  • Tsutsui, J., Kadomatsu, K., Matsubara, S., Nakagawara, A., Hamanoue, M., Takao, S., Shimazu, H., Ohi, Y. and Muramatsu, T. (1993) A new family of heparin-binding growth differentiation factors : increased midkine expression in Wilms' tumor and other human carcinomas. Cancer Res. 53, 1281-1285. [PMID: 8383007]
  • Michikawa, M., Kikuchi, S., Muramatsu, H., Muramatsu, T. and Kim, S.U. (1993) Retinoic acid responsive gene product, midkine (MK), has neurotrophic functions for mouse spinal cord and dorsal root ganglion neurons in culture. J. Neurosci. Res., 35, 530-539. [PMID: 8377224]
  • Satoh, J., Muramatsu, H., Moretto, G., Muramatsu, T., Chang, H.J., Kim, S.T., Cho, J.M. and Kim, S.U. (1993) Midkine that promotes survival of human neurons is produced by fetal human astrocytes in culture. Dev. Brain Res. 75, 201-205. [PMID: 8261612]
  • Yasuhara, O., Muramatsu, H., Kim, S. U., Muramatsu, T., Maruta, H. and McGeer, P. L. (1993) Midkine, a novel neurotrophic factor, is present in senile plaques of Alzheimer disease. Biochem. Biophys. Res. Commun. 192, 246-251. [PMID: 8476427]
  • Muramatsu, H., Shirahama, H., Yonezawa, S., Maruta, H. and Muramatsu, T.(1993) Midkine (MK), a retinoic acid-inducible growth/differentiation factor : immunochemical evidence for the function and distribution. Dev. Biol. 159, 392-402. [PMID: 8405666]
  • Fabri, L., Maruta, H., Muramatsu, H., Muramatsu, T., Simpson, R.J., Burgess, A.W. and Nice, E.C. (1993) Structural characterization of native and recombinant forms of the neurotrophic cytokine MK. J. Chromatog. 646, 213-226. [PMID: 8408430]
  • Uehara, K., Matsubara, S., Kadomatsu, K., Tsutsui, J. and Muramatsu, T. (1992) Genomic structure of human midkine (MK), a retinoic acid-responsive growth / differentiation factor. J. Biochem. 111, 563-567. [PMID: 1639750]
  • Kaname, T., Kuwano, A., Murano, I., Uehara, K., Muramatsu, T. and Kajii, T. (1993) Midkine gene (MDK), a gene for prenatal differentiation and neuroregulation, maps to band 11p11.2 by fluorescence in situ hybridization. Genomics 17, 514-515. [PMID: 8406506]
  • Garver, R. I., Jr., Chan, C. S. and Milner, P. G. (1993) Reciprocal expression of pleiotrophin and midkine in normal versus malignant lung tissues. Am. J. Respir. Cell Mol. Biol. 9, 463-466. [PMID: 8217186]
  • Garver, R. I. Jr., Radford, D. M., Donis-Keller, H., Wick, M. R. and Milner, P. G. (1994) Midkine and pleiotrophin expression in normal and malignant breast tissue. Cancer 74, 1584-1590. [PMID: 7520350]
  • Muramatsu, H., Inui, T., Kimura, T., Sakakibara, S., Song, X., Murata, H. and Muramatsu, T. (1994) Localization of heparin-binding, neurite outgrowth and antigenic regions in midkine molecule. Biochem. Biophys. Res. Commun. 203, 1131-1139. [PMID: 8093031]
  • Matsubara, S., Take, M., Pedraza, C. and Muramatsu, T. (1994) Mapping and characterization of a retinoic acid-responsive enhancer of midkine, a novel heparin binding growth / differentiation factor with neurotrophic activity. J. Biochem. 115, 1088-1096. [PMID: 7982887]
  • Unoki, K., Ohba, N., Arimura, H., Muramatsu, H. and Muramatsu, T. (1994) Rescue of photoreceptors from the damaging effects of constant light by midkine , a retinoic acid responsive gene product. Invest. Ophthalmol. Vis. Sci. 35, 4063-4068. [PMID: 7960588]
  • Take, M., Tsutsui, J., Obama, H., Ozawa, M., Nakayama, T., Maruyama, I., Arima, T. and Muramatsu, T. (1994) Identification of nucleolin as a binding protein for midkine (MK) and heparin-binding growth-associated molecule (HB-GAM). J.Biochem. 116, 1063-1068. [PMID: 7896734]
  • Matsumoto, K., Wanaka, A., Takatsuji, K., Muramatsu, H., Muramatsu, T. and Tohyama, M. (1994) A novel family of heparin-binding growth factors, pleiotrophin and midkine, is expressed in the developing rat cerebral cortex. Dev. Brain Res. 79, 229-241. [PMID: 7955321]
  • Matsumoto, K., Wanaka, A., Mori, T., Taguchi, A., Ishii, N., Muramatsu, H., Muramatsu, T. and Tohyama, M. (1994) Localization of pleiotrophin and midkine in the postnatal developing cerebellum. Neurosci. Lett. 179, 216-220. [PMID: 7824199]
  • Kojima, S., Muramatsu, H., Amanuma, H., and Muramatsu, T. (1995) Midkine enhances fibrinolytic activity of bovine endothelial cells. J. Biol. Chem. 270, 9590-9596 [PMID: 7721890]
  • Mitsiadis, T.A., Muramatsu, T., Muramatsu, H. and Thesleff, I. (1995) Midkine (MK), a heparin-binding growth/differentiation factor, is regulated by retinoic acid and epithelial-mesenchymal interactions in the developing mouse tooth, and affects cell proliferation and morphogenesis. J. Cell Biol. 129, 267-281. [PMID: 7698992]
  • Mitsiadis, T.A., Salmivirta, M., Muramatsu, T., Muramatsu, H., Rauvala, H., Lehtonen, E., Jalkanen, M. and Thesleff, I. (1995) Expression of the heparin-binding cytokines, midkine (MK) and HB-GAM (pleiotrophin) is associated with epithelial-mesenchymal interactions during fetal development and organogenesis, Development 121, 37-51. [PMID: 7867507]
  • Nakagawara, A., Milbrandt, J., Muramatsu, T., Deuel, T.F., Zhao, H., Cnaan, A. and Brodeur, G.M. (1995) Differential expression of pleiotrophin and midkine in advanced neuroblastomas. Cancer Res. 55, 1792-1797. [PMID: 7712489]
  • Aridome, K., Tsutsui, J., Takao, S., Kadomatsu, K., Ozawa, M., Aikou, T. and Muramatsu, T.(1995) Increased midkine gene expression in human gastrointestinal cancers. Jap. J. Cancer Res. 86, 655-661. [PMID: 7559083]
  • Yoshida, Y., Goto, M., Tsutsui, J., Ozawa, M., Sato, E., Osame, M. and Muramatsu, T. (1995) Midkine is present in the early stage of cerebral infarct. Dev. Brain Res. 85, 25-30. [PMID: 7781164]
  • Obama, H., Tsutsui, J., Ozawa, M., Yoshida, H., Osame, M. and Muramatsu, T. (1995) Midkine (MK) and pleiotrophin (PTN) expression in extraembryonic tissues, amniotic fluid and cerebrospinal fluid during mouse embryogenesis. J. Biochem. 118, 88-93. [PMID: 8537330]
  • Kojima, T., Katsumi, A., Yamazaki, T., Muramatsu, T., Nagasaka, T., Ohsumi, K. and Saito, H. (1996) Human ryudocan from endothelial-like cells binds basic fibroblast growth factor, midkine, and tissue factor pathway inhibitor. J. Biol. Chem. 271, 5914-5920. [PMID: 8621465]
  • Kaneda, N., Talukder, A.H., Ishihara, M., Hara, S., Yoshida, K. and Muramatsu, T. (1996) Structural characteristics of heparin-like domain required for interaction of midkine with embryonic neurons. Biochem. Biophys. Res. Commun. 220, 108-112. [PMID: 8602827]
  • Inui, T., Bodi, J., Kubo, S., Nishio, H., Kimura, T., Kojima, S., Maruta, H., Muramatsu, T. and Sakakibara, S. (1996) Solution synthesis of human midkine, a novel heparin binding neurotrophic factor consisting of 121 amino acid residues with five disulphide bonds, J. Peptide Sci. 2, 28-39. [PMID: 9225243]
  • Adachi, Y., Matsubara, S., Pedraza, C., Ozawa, M., Tsutsui, J., Takamatsu, H., Noguchi, H., Akiyama, T. and Muramatsu, T. (1996) Midkine as a novel target gene for the Wilms' tumor suppressor gene (WT1). Oncogene 13, 2197-2203. [PMID: 8950987]
  • Muramatsu, H., Song, X., Koide, N., Hada, H., Tsuji, T., Kadomatsu, K., Inui, T., Kimura, T., Sakakibara, S. and Muramatsu, T. (1996) Enzyme-linked immunoassay for midkine and its application to evaluation of midkine levels in developing mouse brain and in sera from patients with hepatocellular carcinomas. J. Biochem. 119, 1171-1175. [PMID: 8827454]
  • O'Brien, T., Cranston, D., Fuggle, S., Bicknell, R. and Harris, A.L. (1996) The angiogenic factor midkine is expressed in bladder cancer, and overexpression correlates with a poor outcome in patients with invasive cancers. Cancer Res. 56, 2515-2518. [PMID: 8653688]
  • Kaname, T., Kadomatsu, K., Aridome, K., Yamashita, S., Sakamoto, K., Ogawa, M., Muramatsu, T. and Yamamura, K. (1996) The expression of truncated MK in human tumors. Biochem. Biophys. Res. Commun. 219, 256-260. [PMID: 8619817]
  • Kadomatsu, K., Hagihara, M., Akhter, S., Fan, Q-W., Muramatsu, H. and Muramatsu, T. (1997) Midkine induces the transformation of NIH3T3 cells. Brit. J. Cancer 75, 354-359. [PMID: 9020479]
  • Kojima, S., Inui, T., Muramatsu, H., Suzuki, Y., Kadomatsu, K., Yoshizawa, M., Hirose, S., Kimura, T., Sakakibara, S. and Muramatsu, T. (1997) Dimerization of midkine by tissue transglutaminase and its functional implication. J. Biol. Chem. 272, 9410-9416. [PMID: 9083079]
  • Zhou, H., Muramatsu, T., Halfter, W., Tsim, K. W. K. and Peng H. B. (1997) A role of midkine in the development of the neuromuscular junction. Mol. Cell. Neurosci. 10, 56-70. [PMID: 9361288]
  • Takada, T., Toriyama, K., Muramatsu, H., Song, X. J., Torii, S. and Muramatsu, T. (1997) Midkine, a retinoic acid-inducible heparin-binding cytokine in inflammatory responses: chemotactic activity to neutrophils and association with inflammatory synovitis. J. Biochem. 122, 453-458. [PMID: 9378726]
  • Iwasaki, W., Nagata, K., Hatanaka, H., Inui, T., Kimura, T., Muramatsu, T., Yoshida, K., Tasumi, M. and Inagaki, F. (1997) Solution structure of midkine, a new heparin-binding growth factor. EMBO J. 16, 6936-6946. [PMID: 9384573]
  • Nakanishi, T., Kadomatsu, K., Okamoto, T., Ichihara-Tanaka, K., Kojima, T., Saito, H., Tomoda, Y. and Muramatsu, T. (1997) Expression of syndecan-1 and -3 during embryogenesis of the central nervous system in relation to binding with midkine. J. Biochem. 121, 197-205. [PMID: 9089390]
  • Asai, T., Watanabe, K., Ichihara-Tanaka, K., Kaneda, N., Kojima, S., Iguchi, A., Inagaki, F. and Muramatsu, T. (1997) Identification of heparin-binding sites in midkine and their role in neurite-promotion. Biochem. Biophys. Res. Commun. 236, 66-70. [PMID: 9223427]
  • Choudhuri R., Zhang, H. T., Donnini, S., Ziche, M. and Bicknell, R. (1997) An angiogenic role for the neurokines midkine and pleiotrophin in tumorigenesis. Cancer Res. 57, 1814-1819. [PMID: 9135027]
  • Sun X.-Z., Inoue, M., Fukui, Y., Hisano, S., Sawada, K., Muramatsu, H. and Muramatsu, T. (1997) An immunohistochemical study of radial glial cells in the mouse brain prenatally exposed to γ-irradiation. J. Neuropathol. Exp. Neurol. 56, 1339-1348. [PMID: 9413282]
  • Mishima, K., Asai, A., Kadomatsu, K., Ino, Y., Nomura, K., Narita, Y., Muramatsu, T. and Kurino, T. (1997) Increased expression of midkine during the progression of human astrocytomas. Neurosci. Lett. 233, 29-32. [PMID: 9324232]
  • Obama, H., Biro, S., Tashiro, T., Tsutsui, J., Ozawa, M., Yoshida, H., Tanaka, H. and Muramatsu, T. (1998) Midkine expression in the heart is induced by myocardial infarction. Anticancer Res. 18, 145-152. [PMID: 9568069]
  • Nakamura, E., Kadomatsu, K., Yuasa, S., Muramatsu, H., Mamiya, T., Nabeshima, T., Fan, Q.W., Ishiguro, K., Igakura, T., Matsubara, S., Kaname, T., Horiba, M., Saito, H. and Muramatsu, T. (1998) Disruption of the midkine gene (Mdk) resulted in altered expression of a calcium binding protein in the hippocampus of infant mice and their abnormal behaviour. Genes Cells 3, 811-822. [PMID: 10096022]
  • Yokota, C., Takahashi, S., Eisaki, A., Asashima, M., Akhter, S., Muramatsu, T. and Kadomatsu, K. (1998) Midkine counteracts the activin signal in mesoderm induction and promotes neural formation. J. Biochem. 123, 339-346. [PMID: 9538212]
  • Yu, G.S., Hu, J. and Nakagawa, H. (1998) Inhibition of b-amyloid cytotoxicity by midkine. Neurosci. Lett. 254, 125-128. [PMID: 10214973]
  • Maeda, N., Ichihara-Tanaka, K., Kimura, T., Kadomatsu, K., Muramatsu, T. and Noda, M. (1999) A receptor-like protein -tyrosine phosphatase PTPζ/RPTPβ binds a heparin- binding growth factor midkine. Involvement of arginine 78 of midkine in the high affinity binding to PTPζ. J. Biol. Chem. 274, 12474-12479. [PMID: 10212223]
  • Ye, C., Qi, M., Fan, Q.-W., Ito, K., Akiyama, S., Kasai, Y., Matsuyama, M., Muramatsu, T. and Kadomatsu, K. (1999) Expression of midkine in the early stage of carcinogenesis in human colorectal cancer. Brit. J. Cancer 79, 179-184. [PMID: 10408712]
  • Konishi, N., Nakamura, M., Nakaoka, S., Hiasa, Y., Cho, M., Uemura, H., Hirao, Y., Muramatsu, T. and Kadomatsu, K. (1999) Immunohistochemical analysis of midkine expression in human prostate carcinoma. Oncology 57,253-257. [PMID: 10545795]
  • Owada, K., Sanjo, N., Kobayashi, T., Mizusawa, H., Muramatsu, H., Muramatsu, T. and Michikawa, M. (1999) Midkine inhibits caspase-dependent apoptosis via the activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase in cultured neurons. J. Neurochem. 73, 2084-2092. [PMID: 10537068]
  • Ohta, S., Muramatsu, H., Senda, T., Zou, K., Iwata, H. and Muramatsu, T. (1999) Midkine is expressed during repair of bone fracture and promotes chondrogenesis. J. Bone Miner. Res. 14, 1132-1144. [PMID: 10404013]
  • Kato, S., Ishihara, K., Shinozawa, T., Yamaguchi, H., Asano, Y., Saito, M., Kato, M., Terada, T., Awaya, A., Hirano, A., Dickson, D.W., Yen, S.H. and Ohama, E. (1999) Monoclonal antibody to human midkine reveals increased midkine expression in human brain tumors. J. Neuropathol. Exp. Neurol. 58, 430-441. [PMID: 10331431]
  • Ikematsu, S., Yano, A., Aridome, K., Kikuchi, M., Kumai, H., Nagano, H., Okamoto, K., Oda, M., Sakuma, S., Aikou, T., Muramatsu, H., Kadomatsu, K. and Muramatsu, T. (2000) Serum midkine levels are increased in patients with various types of carcinomas. Brit. J. Cancer. 83, 701-706. [PMID: 10952771]
  • Zou, K., Muramatsu, H., Ikematsu, S., Sakuma, S., Salama, R.H., Shinomura, T., Kimata, K. and Muramatsu, T. (2000) A heparin-binding growth factor, midkine, binds to a chondroitin sulfate proteoglycan, PG-M/versican. Eur. J. Biochem. 267, 4046-4053. [PMID: 10866805]
  • Ueoka, C., Kaneda, N., Okazaki, I., Nadanaka, S., Muramatsu, T., and Sugahara, K. (2000) Neuronal cell adhesion mediated by the heparin-binding neuroregulatory factor, midkine, is specifically inhibited by chondroitin sulfate E. Structural and functional implication of the oversulfated chondroitin sulfate. J. Biol. Chem. 275, 37407-37413. [PMID: 10978312]
  • Horiba, M., Kadomatsu, K., Nakamura, E., Muramatsu, H., Ikematsu, S., Sakuma, S., Hayashi, K., Yuzawa, Y., Matsuo, S., Kuzuya, M., Kaname, T., Hirai, M., Saito, H. and Muramatsu, T. (2000) Neointima formation in a restenosis model is suppressed in midkine-deficient mice. J. Clin. Invest. 105, 489-495. [PMID: 10683378]
  • Kurosawa, N., Kadomatsu, K., Ikematsu, S., Sakuma, S., Kimura, T. and Muramatsu, T. (2000) Midkine binds specifically to sulfatide: the role of sulfatide in cell attachment to midkine-coated surfaces. Eur. J. Biochem. 267, 344-351. [PMID: 10632704]
  • Muramatsu, H., Zou, K., Sakaguchi, N., Ikematsu, S., Sakuma, S. and Muramatsu, T. (2000) LDL-receptor related protein as a component of the midkine receptor. Biochem. Biophys. Res. Commun. 270, 936-941. [PMID: 10772929]
  • Ikeda, S., Ichihara-Tanaka, K., Azuma, T., Muramatsu, T. and Yamada, M. (2000) Effects of midkine during in vitro maturation of bovine oocytes on subsequent developmental competence. Biol. Reprod. 63, 1067-1074. [PMID: 10993828]
  • Adachi, Y., Reynolds, P. N., Yamamoto, M., Grizzle, W. E., Overturf, K., Matsubara, S., Muramatsu, T. and Curiel, D. T. (2000) Midkine promoter-based adenoviral vector gene delivery for pediatric solid tumors. Cancer Res. 60, 4305-4310. [PMID: 10969765]
  • Kato, M., Maeta, H., Kato, S., Shinozawa, T., and Terada, T. (2000) Immunohistochemical and in situ hybridization analyses of midkine expression in thyroid papillary carcinoma. Mod. Pathol. 13, 1060-1065. [PMID: 11048798]
  • Sumi, Y., Muramatsu, H., Hata, K., Ueda, M. and Muramatsu, T. (2000) Midkine enhances early stages of collagen gel contraction. J. Biochem. 127, 247-251. [PMID: 10731691]
  • Qi, M., Ikematsu, S., Ichihara-Tanaka, K., Sakuma, S. Muramatsu, T. and Kadomatsu, K. (2000) Midkine rescues Wilmsユ tumor cells from cisplatin-induced apoptosis: regulation of Bcl-2 expression by midkine. J. Biochem. 127,269-277. [PMID: 10731694]
  • Adachi, Y., Reynolds, P. N., Yamamoto, M., Wang, M., Takayama, K., Matsubara, S., Muramatsu, T. and Curiel, D. T. (2001) A midkine promoter-based conditionally replicative adenovirus for treatment of pediatric solid tumors and bone marrow tumor purging. Cancer Res. 61,7882-7888. [PMID: 11691808]
  • Miyauchi, M., Yoshida, Y., Tada, Y., Narita, M., Maeda, T., Bahar, R., Kadomatsu, K., Muramatsu, T., Matsubara, S., Nakagawara, A., Sakiyama, S. and Tagawa, M. (2001) Expression of herpes simplex virus-thymidine kinase gene controlled by a promoter region of the midkine gene confers selective cytotoxicity to ganciclovir in human carcinoma cells. Int. J. Cancer 91, 723-727. [PMID: 11267987]
  • Callebaut, C., Nisole, S., Briand, J. P., Krust, B. and Hovanessian, A. G. (2001) Inhibition of HIV infection by the cytokine midkine. Virology 281, 248-264. [PMID: 11277697]
  • Winkler, C. and Moon, R. T. (2001) Zebrafish mdk2, a novel secreted midkine, participates in posterior neurogenesis. Dev. Biol. 229, 102-118. [PMID: 11133157]
  • Kurosawa, N., Chen, G., Kadomatsu, K., Ikematsu, S., Sakuma S. and Muramatsu, T. (2001) Glypican-2 binds to midkine: The role of glypican-2 in neuronal cell adhesion and neurite outgrowth. Glycoconj. J. 18, 499-507. [PMID: 12084985]
  • Sato, W., Kadomatsu, K., Yuzawa, Y., Muramatsu, H., Hotta, N., Matsuo, S. and Muramatsu T. (2001) Midkine is involved in neutrophil infiltration into the tubulointerstitium in ischemic renal injury. J. Immunol. 167, 3463-3469. [PMID: 11544339]
  • Mashour, G. A., Ratner, N., Khan, G. A., Wang, H. L., Martuza, R. L. and Kurtz, A. (2001) The angiogenic factor midkine is aberrantly expressed in NF1-deficient Schwann cells and is a mitogen for neurofibroma-derived cells. Oncogene 20, 97-105. [PMID: 11244508]
  • Takei, Y., Kadomatsu, K., Matsuo, S., Itoh, H., Nakazawa, K., Kubota,S. and Muramatsu, T. (2001) Antisense oligodeoxynucleotide targeted to midkine, a heparin-binding growth factor, suppresses tumorigenicity of mouse rectal carcinoma cells. Cancer Res. 61, 8486-8491. [PMID: 11731432]
  • Salama, R. H. M., Muramatsu, H., Zou, K., Inui, T., Kimura, T. and Muramatsu, T. (2001) Midkine binds to 37-kDa laminin binding protein precursor, leading to nuclear transport of the complex. Exp. Cell Res. 270,13-20. [PMID: 11597123]
  • Qi, M., Ikematsu, S., Maeda, N., Ichihara-Tanaka, K., Sakuma, S., Noda, M., Muramatsu, T. and Kadomatsu, K. (2001) Haptotactic migration induced by midkine: Involvement of protein-tyrosine phosphatasez, mitogen-activated protein kinase and phosphatidylinositol 3-kinase. J. Biol. Chem. 276, 15868-15875. [PMID: 11340082]
  • Yoshida, Y., Ikematsu, S., Moritoyo, T., Goto, M., Tsutsui, J., Sakuma, S., Osame, M. and Muramastu, T. (2001) Intraventricular administration of the neurotrophic factor midkine ameliorates hippocampal delayed neuronal death following transient forebrain ischemia in gerbils. Brain Res. 894, 46-55 [PMID: 112459814]
  • Shibata, Y., Muramatsu, T., Hirai, M., Inui, T., Kimura, T., Saito, H., McCormick, L.M., Bu, G. and Kadomatsu, K. (2002) Nuclear targeting by the growth factor midkine. Mol. Cell. Biol. 22, 6788-6796. [PMID: 12215536]
  • Sumi, Y., Muramatsu, H., Takei, Y., Hata, K., Ueda, M. and Muramatsu, T. (2002) Midkine, a heparin-binding growth factor promotes growth and glycosaminoglycan synthesis of endothelial cells through its action on smooth muscle cells in an artificial blood vessel model. J. Cell Sci.115, 2659-2667. [PMID: 12077357]
  • Stoica, G.E., Kuo, A., Powers, C., Bowden, E.T., Sale, E.B., Riegel, A.T. and Wellstein A. (2002) Midkine binds to anaplastic lymphoma kinase (ALK) and acts as a growth factor for different cell types. J. Biol. Chem. 277, 35990-35998. [PMID: 12122009]
  • Ikematsu, S., Nakagawara, A., Nakamura, Y., Sakuma, S., Wakai, K., Muramatsu, T. and Kadomatsu, K. (2003) Correlation of elevated level of blood midkine with poor prognostic factors of human neuroblastomas. Br. J. Cancer 88, 1522-1526. [PMID: 12771916]
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  • Terao, S., Shirakawa, T., Kubo, S, Bishunu, A., Lee, S.J., Goda, K., Tsukuda, M., Hamada, K., Tagawa, M., Takenaka, .A, Fujisawa, M., and Gotoh, A. (2007) Midkine promoter-based conditionally replicative adenovirus for targeting midkine-expressing human bladder cancer model. Urology, 70, 1009-1013. [PMID: 17919690]
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Edited by  T. Muramatsu